Vol. 31 No. 2 (2023), Case Reports

Vol. 31 No. 2 (2023)

A case of SAPHO syndrome treated with zoledronic acid and hydroxychloroquine

Case Reports

DOI: https://doi.org/10.35465/31.2.2023.pp58-66

Published 31-08-2023

Sevdalina Lambova⁺⁻
G. Hadzhigeorgiev⁺⁻
G. Gelov⁺⁻
P. Uchikov⁺⁻

Sevdalina Lambova

Department of Propedeutics of Internal Diseases “Prof Dr Anton Mitov”, Faculty of Medicine, Medical University – Plovdiv

G. Hadzhigeorgiev

Department in Imaging Diagnostics, MHAT “Sveti Mina” – Plovdiv

G. Gelov

Department in Surgery, MHAT – Haskovo

P. Uchikov

Department of Special Surgery, Faculty of Medicine, Medical University – Plovdiv

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Keywords

SAPHO syndrome
zolendronic acid
hydroxychloroquine

How to Cite

Lambova, S., Hadzhigeorgiev, G., Gelov, G., & Uchikov, P. (2023). A case of SAPHO syndrome treated with zoledronic acid and hydroxychloroquine. Rheumatology (Bulgaria), 31(2), 58-66. https://doi.org/10.35465/31.2.2023.pp58-66

Abstract

Abstract: SAPHO syndrome is characterized with a set of symptoms including skin lesions, osteoarticular manifestations like aseptic osteitis (of the anterior chest wall or other skeletal sites), peripheral synovitis. Due to the lack of randomized clinical trials and low prevalence of the condition, there are no established treatment guidelines for SAPHO syndrome. Here, we report a clinical case of SAPHO syndrome with osteitis of the sternum and palmoplantar pustulosis successfully treated with zoledronic acid and hydroxychloroquine.

DOI: https://doi.org/10.35465/31.2.2023.pp58-66

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