Correlations between the severity of neurological deficit and anatomical localization in cerebral venous thrombosis patients – a retrospective study
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Keywords

anatomical localization, clinical manifestation, CVT

How to Cite

[1]
Stratieva, S., Valova, T., Prinova, K. and Pashkunova, S. 2021. Correlations between the severity of neurological deficit and anatomical localization in cerebral venous thrombosis patients – a retrospective study. Revmatologiia (Bulgaria). 28, 4 (Feb. 2021), 19-30. DOI:https://doi.org/10.35465/28.4.2020.pp19-30.

Abstract

Abstract 

The aim of this study is to examine the relationship between anatomical localization of thrombosis and the severity of neurological deficits in patients with cerebral venous thrombosis (CVT). The diagnostic method is MR venography. The study is retrospective, with 49 patients included, diagnosed and followed in Military Medical Academy, Sofia, Clinic of Neurological Diseases for10 years period between 2005 and 2015. Patients were divided into groups, according to the severity of the neurological deficit and the anatomical localization of thrombosis. We searched for a correlation between these two indicators. No statistically significant dependence was found in the analysis.

Keywords: anatomical localization, clinical manifestation, CVT

 

https://doi.org/10.35465/28.4.2020.pp19-30
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PDF BG (Български)

References

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  26. Agnelli, G., M. Verso. Epidemiology of cerebral vein and sinus thrombosis. Front Neurol Neurosci 2008; 23:16-22.
  27. Baglin, T. (2012). "Inherited and acquired risk factors for venous thromboembolism". Semin Respir Crit Care Med 33 (2): 127–37.
  28. Stam, J. Thrombosis of the cerebral veins and sinuses, N Engl J Med. 2005; 352:1791–1798.
  29. Ferro, JM., Canhao P, Stam J et al. SE; ISCVT Investigators. Delay in the diagnosis of cerebral vein and dural sinus thrombosis: influence on outcome. Stroke. 2009; 40: 3133–3138.
  30. Penka, A. Atanassova, Radka I. et al. Cerebral Venous Sinus Thrombosis - Diagnostic Strategies and Prognostic Models: A Review Venous Thrombosis – Principles and Practice 129-158.
  31. Ferro, JM., Canhao P, Bousser MG et al. ISCVT Investigators. Early seizures in acute cerebral vein and dural sinus thrombosis (CVT). Prevalence, risk of early recurrence and associated conditions. Cerebrovasc Dis 2006; 21(suppl 4): 39.
  32. Ferro, JM., Canhao P, Bousser MG et al. ISCVT Investigators. Cerebral vein and dural sinus thrombosis in elderly patients. Stroke. 2005; 36: 1927–1932.
  33. Ferro, JM., Canhao P, Bousser MG et al. ISCVT Investigators. Early seizures in cerebral vein and dural sinus thrombosis: risk factors and role of antiepileptics. Stroke. 2008; 39: 1152–1158.
  34. Ferro, JM., Canhao P, Stam J, et al. SCVT Investigators. Prognosis of cerebral vein and dural sinus thrombosis: results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke. 2004; 35: 664–670.
  35. Bousser MG, Russell RR. Pathology and pathogenesis of venous infarction. In: Bousser MG, ed. Cerebral Venous Thrombosis. Paris VI Univ, Paris, France: WB Saunders Company; 1997:20-21.
  36. Usman U. and Wasay M., Mechanism of neuronal injury in cerebral venous thrombosis, Journal of the Pakistan Medical Association, vol. 56, no. 11, pp. 509-512, 2006.
  37. Forbes KP, Pipe JG, Heiserman JE. Evidence for cytotoxic edema in the pathogenesis of cerebral venous infarction. AJNR Am J Neuroradiol. 2001; 22:450-455.
  38. Leys, D., Cordonnier C. Cerebral venous thrombosis: update on clinical manifestations, diagnosis and management. Ann Indian Acad Neurol. 2008; 11:S79 –S87.
  39. De Bruijn, SF., Stam J, Koopman MM et al. Case-control study of risk of cerebral sinus thrombosis with third generation-oral contraceptives. Cerebral Venous Sinus Thrombosis Study Group. BMJ 1998; 316(7131): 589–592.
  40. Ferraresi, P., Marchetti G, Legnani C, et al. The heterozygous 20210 G/A prothrombin genotype is associated with early venous thrombosis in inherited thrombophilia and is not increased in frequency in artery disease. Arterioscler Thromb Vasc Biol 1997; 17(11):2418-2422.
  41. Martinelli, I., Battaglioli T, Pedotti P et al. Hyperhomocysteinemia in cerebral vein thrombosis. Blood. 2003; 102: 1363–1366.
  42. Martinelli, I., Bucciarelli P, Mannucci PM (2010). "Thrombotic risk factors: basic pathophysiology". Crit Care Med 38 (2 Suppl): S3–9.
  43. Хаджиев, Д. Тромбози на мозъчните вени и на дуралните синуси и редки съдови синдроми. В: Ръководство по неврология, том 1. (Хаджиев Д, Георгиев Ив., ред.), София: Медицина и физкултура, 1988, 316-321.
  44. Ribes M. Des recherches faites sur la phlebite. Revue Medicale Francaise et Etrangere et Journal de Clinique de L’Hotel-Dieu et de la Charite de Paris, vol. 3, pp.5-41, 1825.
  45. Paciaroni, M., Palmerini, F., Bogousslavsky, J. Clinical presentations of cerebral vein and sinus thrombosis. Front Neurol Neurosci 2008; 23: 77-88.
  46. Cumurciuc, R. I., Crassard, M., Sarov, D. et al. Headache as the only neurological sign of cerebral venous thrombosis: a series of 17 cases. Journal of Neurology, Neurosurgery and Psychiatry, vol. 76, no. 8, pp. 1084–1087, 2005.
  47. Janghorbani, M., Zare M, Saadatnia M et al. Cerebral vein and dural sinus thrombosis in adults in Isfahan, Iran: frequency and seasonal variation. Acta Neurol Scand. 2008;117: 117–121.
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