Psoriasis is a disease that affects 2-3% of the world population. 30-40% of the affected patients develop psoriatic arthritis. Almost 50% of them are women, with 75% under the age of 40 years. Treatment of psoriasis and psoriatic arthritis requires knowledge of the reproductive aspects of the disease. There are treatment-related risks that may affect pregnancy planning and pregnancy itself. Local (topical) and systemic therapies may cause damage to the mother and the fetus. Female patients with psoriatic arthritis at reproductive age pose questions that can be resolved by a specialist-rheumatologist in collaboration with other professionals.