Abstract
Underestimation of the disease osteoporosis in men is a serious problem, as osteoporotic fractures among men are frequent and they are accompanied by serious complications. Conducting DXA scans in men in Bulgaria is important to determine the state of their bone health.
The aim of the study was to assess the bone mineral density (BMD) and T-score of the lumbar spine and of the hip through dual-energy X-ray absorptiometry (DXA) in men and to compare their values in different age groups.
Object of the study. Height, weight, body mass index (BMI) were assessed in 359 men with a mean age of 56 years (yrs.) ± 14 yrs., BMD and T-score of the lumbar spine and femoral neck were also examined.
Methodology. Men are divided into the following age decades: 20-29 yrs., 30-39 yrs., 40-49 yrs., 50-59 yrs., 60-69 yrs., 70-79 yrs. and ≥80 yrs. Statistical program SPSS version 19.0 was used to access the data. The ANOVA test analyzes was applied to investigate if there are any statistically significant differences in BMD and T-score of the lumbar spine and femoral neck between the different age decades.
Results and conclusions. 264 men were evaluated for total BMD of the lumbar spine and 95 men had results for BMD of the femoral neck. The mean total BMD of the lumbar spine differed significantly between the individual age decades in men (p = 0.000). The mean BMD values of the femoral neck did not differ significantly in the different age decades in men (p = 0.07). 34 of 264 men (12.9%) were diagnosed with lumbar spine osteoporosis and 13 out of 93 men (14%) were diagnosed with femoral neck osteoporosis. The data obtained show a widespread prevalence of osteoporosis among men with a predominance of low values of BMD on the axial skeleton in the age range between 60 and 79 years.
References
-
1. Saljoughian Manouchehr. Male Osteoporosis: An Overview. Men s health US Pharm. 3013;38(9):HS-20-HS-24.
2. Pasco J.A., Nicholson G.C., Kotowicz M.A., Cohort Profile: Geelong Osteoporosis Study, International Journal of Epidemiology, Volume 41, Issue 6, December 2012, Pages 1565–1575.
3. Kanis JA, Norton N, Harvey NC, et al. SCOPE 2021: a new scorecard for osteoporosis in Europe. Arch Osteoporos. 2021;16(1):82.
4. Nowotny, J., Bischoff, F., Ahlfeld, T. et al. Biomechanical comparison of bi- and tricortical k-wire fixation in tension band wiring osteosynthesis. Eur J Med Res 24, 33 (2019).
5. Biewener, A., Bischoff, F., Rischke, T. et al. Instability of the proximal radioulnar joint in Monteggia fractures—an experimental study. J Orthop Surg Res 14, 392 (2019).
6. Hernlund E, Svedbom A, IvergÅrd M, et al. Osteoporosis in the European Union: medical management, epidemiology and economic burden. A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch Osteoporos. 2013;8(1–2):136.
7. Nelson HD, Haney EM, Dana T, Bougatsos C, Chou R. Screening for osteoporosis: an update for the US. Preventive Services Task Force. Ann Intern Med. 2010;153(2):99–111.
8. Melton LJ 3rd, Lieber MM, Atkinson EJ и др. Риск от фрактури при мъже с рак на простатата: популационно проучване. J Bone Miner Res . 2011;26(8):1808–1815.
9. Ralston, S.H.; Uitterlinden, A.G. Genetics of osteoporosis. Endocr. Rev. 2010, 31, 629–662.
10. Drake MT, Murad MH, Mauck KF, et al. Clinical review. Risk factors for low bone mass-related fractures in men: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2012;97(6):1861–1870.
11. Hillier TA, Cauley JA, Rizzo JH, et al. WHO absolute fracture risk models (FRAX): do clinical risk factors improve fracture prediction in older women without osteoporosis?. J Bone Miner Res. 2011;26(8):1774-1782.
12. Hans, D. B., Kanis, J. A., Baim, S., Bilezikian, J. P., Binkley, N., Cauley, J. A., Compston, J. E., Cooper, C., Dawson-Hughes, B., El-Hajj Fuleihan, G., Leslie, W. D., Lewiecki, E. M., Luckey, M. M., McCloskey, E. V., Papapoulos, S. E., Poiana, C., Rizzoli, R., & FRAX(®) Position Development Conference Members (2011). Joint Official Positions of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(®). Executive Summary of the 2010 Position Development Conference on Interpretation and use of FRAX® in clinical practice. Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry, 14(3), 171–180.
13. Trotter M, Hixon BB. Sequential changes in weight, density, and percentage ash weight of human skeletons from an early fetal period through old age. Anat Rec. 1974 May;179(1):1-18.
14. Wang XF, Duan Y, Beck TJ, Seeman E. Varying contributions of growth and ageing to racial and sex differences in femoral neck structure and strength in old age. Bone. 2005 Jun;36(6):978-86.
15. Kanis JA, Bianchi G, Bilezikian JP, et al. Towards a diagnostic and therapeutic consensus in male osteoporosis. Osteoporos Int. 2011;22(11):2789–2798.
16. Pasco JA, Lane SE, Brennan SL, et al. Fracture risk among older men: osteopenia and osteoporosis defined using cut-points derived from female versus male reference data. Osteoporos Int. 2014;25:857–862.
17. Боянов М , Попиванов П . Разпространение на ниска плътност на костите на предмишницата в българска референтна популация от жени . Osteoporos Int 2002 ; 13: 288 – 295.
18. Боянов М , Христов В . Разпространение на ниска централна костна минерална плътност при български мъже . Journal of Men's Health 2005 ; 2: 318 – 324.
19. Papaioannou A, Morin S, Cheung AM, et al; Scientific Advisory Council of Osteoporosis Canada. 2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary. CMAJ. 2010;182(17):1864–1873.
20. Position Development Conference: Task Force on Normative Databases. J Clin Densitom. 2013;16(4):472–481.
21. Watts NB, Adler RA, Bilezikian JP, et al; Endocrine Society. Osteoporosis in men: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2012;97(6):1802–1822.
22. Margaret J Henry, Julie A Pasco, Geoff C Nicholson, Mark A Kotowicz, Prevalence of osteoporosis in Australian men and women: Geelong Osteoporosis Study, Medical Journal of Australia, 10.5694/mja11.10571, 195, 6, (321-322), (2011).
23. Rinonapoli G, Ruggiero C, Meccariello L, Bisaccia M, Ceccarini P, Caraffa A. Osteoporosis in Men: A Review of an Underestimated Bone Condition. International Journal of Molecular Sciences. 2021; 22(4):2105.
24. Boyanov M, P. Popivanov, N Temelkova Prevalence of low forearm bone mineral density in Bulgarian men: a pilot study The Aging Male, March 2007; 10(1): 9–16.
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